Subwavelength optical microscopy in the far field
نویسندگان
چکیده
منابع مشابه
Subwavelength far - field ultrasound drug - delivery
The theoretical diffraction-limit of resolution for ultrasound imaging has recently been bypassed in-vitro and in-vivo. However, in the context of ultrasound therapy, the precision of therapeutic beams remains bound to the half-wavelength limit. By combining acoustic vaporization of composite droplets and rapid ultrasound monitoring, we demonstrate that ultrasound drug-delivery can be restricte...
متن کاملMaximizing far-field optical microscopy resolution through selected fluorophore transitions
Stimulated emission depletion (STED) microscopy and related nanoscopy techniques, which utilize a saturable optical transition between a bright and a dark state, overcome the diffraction barrier by confining one of the states to an area smaller than the Airy disk. Scanning this area across the specimen yields subdiffraction images by registering inseparable fluorescent markers sequentially in t...
متن کاملFar - Field Optical Nanoscopy
37. E. Evans, Annu. Rev. Biophys. Biomol. Struct. 30, 105 (2001). 38. G. I. Bell, Science 200, 618 (1978). 39. For adhesive interactions important in soft tissues and organs of eukaryotic cell systems, the average times toff° reported for spontaneous dissociation of ligand/receptor bonds range from a fraction of a second to 100 s or more. 40. Because of thermal activation, the appropriate unit ...
متن کاملFar-field optical superlens.
Far-field optical lens resolution is fundamentally limited by diffraction, which typically is about half of the wavelength. This is due to the evanescent waves carrying small scale information from an object that fades away in the far field. A recently proposed superlens theory offers a new approach by surface excitation at the negative index medium. We introduce a far-field optical superlens (...
متن کاملSubdiffraction resolution in far-field fluorescence microscopy.
We overcame the resolution limit of scanning far-field fluorescence microscopy by disabling the fluorescence from the outer part of the focal spot. Whereas a near-UV pulse generates a diffraction-limited distribution of excited molecules, a spatially offset pulse quenches the excited molecules from the outer part of the focus through stimulated emission. This results in a subdiffraction-sized e...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Physical Review A
سال: 2011
ISSN: 1050-2947,1094-1622
DOI: 10.1103/physreva.83.063818